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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
LMNB1
All Species:
22.42
Human Site:
T549
Identified Species:
44.85
UniProt:
P20700
Number Species:
11
Phosphosite Substitution
Charge Score:
0.09
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P20700
NP_005564.1
586
66408
T549
R
S
T
V
F
K
T
T
I
P
E
E
E
E
E
Chimpanzee
Pan troglodytes
XP_517906
586
66445
T549
R
S
T
V
F
K
T
T
I
P
E
E
E
E
E
Rhesus Macaque
Macaca mulatta
XP_001097340
586
66435
T549
R
S
T
V
F
K
T
T
I
P
E
E
E
E
E
Dog
Lupus familis
XP_531892
519
58503
A493
E
E
E
E
E
E
E
A
P
E
V
V
V
E
E
Cat
Felis silvestris
Mouse
Mus musculus
P14733
588
66767
T550
R
S
T
V
F
K
T
T
I
P
E
E
E
E
E
Rat
Rattus norvegicus
P70615
587
66588
T549
R
S
T
V
F
K
T
T
I
P
E
E
E
E
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001506656
591
66278
F558
A
S
Y
S
P
Y
P
F
S
F
P
P
S
S
S
Chicken
Gallus gallus
P14731
584
66512
T548
R
S
T
V
F
K
T
T
V
N
E
G
E
E
E
Frog
Xenopus laevis
P09010
583
66432
N548
R
T
T
I
Y
T
T
N
I
P
E
E
E
F
E
Zebra Danio
Brachydanio rerio
NP_694504
588
66732
A550
R
S
T
V
F
K
T
A
V
E
D
E
D
D
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
P08928
622
71282
S582
D
R
I
K
R
I
V
S
Q
H
T
S
S
S
R
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q21443
566
64066
D541
R
L
E
D
S
E
G
D
T
V
S
S
I
T
V
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.6
99.3
81.5
N.A.
95.9
95.4
N.A.
61.2
79.3
72.5
69.3
N.A.
37.6
N.A.
34.1
N.A.
Protein Similarity:
100
100
99.6
84.6
N.A.
97.6
97.4
N.A.
69
89.5
85.8
84.8
N.A.
59.4
N.A.
51.7
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
6.6
80
60
53.3
N.A.
0
N.A.
6.6
N.A.
P-Site Similarity:
100
100
100
20
N.A.
100
100
N.A.
6.6
86.6
80
86.6
N.A.
6.6
N.A.
13.3
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
9
0
0
0
0
0
0
17
0
0
0
0
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
9
0
0
9
0
0
0
9
0
0
9
0
9
9
9
% D
% Glu:
9
9
17
9
9
17
9
0
0
17
59
59
59
59
67
% E
% Phe:
0
0
0
0
59
0
0
9
0
9
0
0
0
9
0
% F
% Gly:
0
0
0
0
0
0
9
0
0
0
0
9
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
9
0
0
0
0
0
% H
% Ile:
0
0
9
9
0
9
0
0
50
0
0
0
9
0
0
% I
% Lys:
0
0
0
9
0
59
0
0
0
0
0
0
0
0
0
% K
% Leu:
0
9
0
0
0
0
0
0
0
0
0
0
0
0
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% M
% Asn:
0
0
0
0
0
0
0
9
0
9
0
0
0
0
0
% N
% Pro:
0
0
0
0
9
0
9
0
9
50
9
9
0
0
0
% P
% Gln:
0
0
0
0
0
0
0
0
9
0
0
0
0
0
0
% Q
% Arg:
75
9
0
0
9
0
0
0
0
0
0
0
0
0
9
% R
% Ser:
0
67
0
9
9
0
0
9
9
0
9
17
17
17
9
% S
% Thr:
0
9
67
0
0
9
67
50
9
0
9
0
0
9
0
% T
% Val:
0
0
0
59
0
0
9
0
17
9
9
9
9
0
9
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
9
0
9
9
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _